Purification and identification of antimicrobial sesquiterpene lactones from yacon (Smallanthus sonchifolius) leaves.
نویسندگان
چکیده
The extraction of yacon [Smallanthus sonchifolius (Poepp. and Endl.) H. Robinson; Asteraceae] leaves and chromatographic separation yielded two new antibacterial melampolide-type sesquiterpene lactones, 8beta-tigloyloxymelampolid-14-oic acid methyl ester and 8beta-methacryloyloxymelampolid-14-oic acid methyl ester, as well as the four known melampolides, sonchifolin, uvedalin, enhydrin and fluctuanin. The newly identified compound, 8beta-methacryloyloxymelampolid-14-oic acid methyl ester, exhibited potent antimicrobial activity against Bacillus subtilis and Pyricularia oryzae, while 8beta-tigloyloxymelampolid-14-oic acid methyl ester showed lower activity. Fluctuanin exhibited the strongest antibacterial activity against B. subtilis among these six sesquiterpene lactones.
منابع مشابه
Article 14.indd
Smallanthus sonchifolius (Poepp.) H. Rob., Asteraceae, known as yacon, is an herb that is traditionally used for the treatment of diabetes in folk medicine. However, recent studies have demonstrated that this plant has other interesting properties such as anti-microbial and anti-infl ammatory actions. Thus, the purpose of this study was to evaluate the topical anti-infl ammatory property of dif...
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Smallanthus sonchifolius (Poepp.) H. Rob., Asteraceae, known as yacon, is an herb that is traditionally used for the treatment of diabetes in folk medicine. However, recent studies have demonstrated that this plant has other interesting properties such as anti-microbial and anti-infl ammatory actions. Thus, the purpose of this study was to evaluate the topical anti-infl ammatory property of dif...
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Yacon (Smallanthus sonchifolius Poepp.) leaves are a potentially rich source of bioactive compounds, such as phenolic acids and flavonoids. In this study, the effect of the extraction method (ohmic-assisted decoction (OH-DE) and decoction (DE)), yacon cultivar (red and white), and leaf age (young and old) on the quality/quantity of extracted phytochemicals were investigated. Extraction yield, e...
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 67 10 شماره
صفحات -
تاریخ انتشار 2003